Scientists have finally managed to uncover the mechanisms that control the movement of sperm cells when reaching the eggs to membuahinya. The discovery was a new chapter in research on fertility as well as opening the way for treatment and the creation of male contraceptives.
As reported in the February issue of the journal Cell, Dr. Yuriy Kirichok and colleagues from the University of California at San Francisco succeeded in observing the behavior of sperm. Sperm was not immediately bererang shortly after ejaculation. However, when they enter the female reproductive tract, they started swimming and picking up speed when approaching the egg.
Sperm cells apparently have limitations. To be the champion, they must wait for the right moment. The winner is not in motion, but they waited a moment before then swam sporadically reaching the eggs.
According to researchers, the movement of sperm is also affected by the level of acidity (pH) of them internally. A small pores on the surface of sperm cells will determine the pH change that later became pelecut movement in sperm tails.
From previous research it has been revealed that the level of sperm activity is largely determined by internal pH. However, scientists had not yet found a mechanism that can regulate the level of acid or basanya sperm.
In his research, Dr. Yuriy Kirichok found that to raise the pH becomes more alkaline (base), sperm cells have to throw the molecule protons. To achieve this, it can be done through the pores on the surface of sperm cells.
"The concentration of protons in the sperm 1,000 times higher than outside it. Only by opening a pore, proton will come out-we also have identified the molecules that make them out," he said.
Kirichok added, pores proficiency level, or researchers with a term called HV1 proton channels, it seems dikonsidikan in the open position. Pores that can respond to a similar substance called anandamide, which is found in the female reproductive organs and substances that high levels around the egg.
Is the endocannabinoid anandamide, a natural substance that can affect neurons. According to researchers, a substance found in marijuana cannabinoids also had similar effects so that it can explain why the use of marijuana causes infertility in men.
"Marijuana seems to make sperm become activated prematurely, so they burned in a matter of hours," said Dr. Kirichok
As reported in the February issue of the journal Cell, Dr. Yuriy Kirichok and colleagues from the University of California at San Francisco succeeded in observing the behavior of sperm. Sperm was not immediately bererang shortly after ejaculation. However, when they enter the female reproductive tract, they started swimming and picking up speed when approaching the egg.
Sperm cells apparently have limitations. To be the champion, they must wait for the right moment. The winner is not in motion, but they waited a moment before then swam sporadically reaching the eggs.
According to researchers, the movement of sperm is also affected by the level of acidity (pH) of them internally. A small pores on the surface of sperm cells will determine the pH change that later became pelecut movement in sperm tails.
From previous research it has been revealed that the level of sperm activity is largely determined by internal pH. However, scientists had not yet found a mechanism that can regulate the level of acid or basanya sperm.
In his research, Dr. Yuriy Kirichok found that to raise the pH becomes more alkaline (base), sperm cells have to throw the molecule protons. To achieve this, it can be done through the pores on the surface of sperm cells.
"The concentration of protons in the sperm 1,000 times higher than outside it. Only by opening a pore, proton will come out-we also have identified the molecules that make them out," he said.
Kirichok added, pores proficiency level, or researchers with a term called HV1 proton channels, it seems dikonsidikan in the open position. Pores that can respond to a similar substance called anandamide, which is found in the female reproductive organs and substances that high levels around the egg.
Is the endocannabinoid anandamide, a natural substance that can affect neurons. According to researchers, a substance found in marijuana cannabinoids also had similar effects so that it can explain why the use of marijuana causes infertility in men.
"Marijuana seems to make sperm become activated prematurely, so they burned in a matter of hours," said Dr. Kirichok
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